Efforts at prevention of alcohol and other drug problems are often limited to elementary and secondary students, but students in the postsecondary setting also need and can benefit from prevention strategies. Current research shows alcohol and other drugs to be a major problem on postsecondary campuses despite the fact that the purchase and use of alcohol is illegal for many college students and on most campuses. Resilience research shows that promoting positive youth development is an effective means of preventing a variety of problems, including problems with alcohol and other drugs. Deaf students in the postsecondary setting often fall behind in the development process of making connections to healthy people, places, ideas and interests. This paper looks at strategies which can be used in the postsecondary setting to help Deaf and hard of hearing students be prepared to deal with alcohol/drugs and thus be successful in their educational efforts. In addition, institutional policies and practices will be suggested that support a healthy way of life for Deaf postsecondary students.